Antispasmodic Activity of Fractions and Cynaropicrin from Cynara scolymus on Guinea-Pig Ileum
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چکیده
منابع مشابه
Antispasmodic Activity of Persea cordata Vell. Mez. (Lauraceae) Fractions on Guinea Pig Ileum Induced by 5-Hydroxytryptamine and Bradykinin
Problem statement: Persea cordata previously demonstrated antispasmodic action against two neurotransmitters. It is important confirm such action against other neurotransmitters. Approach: Present study described the antispasmodic activity of polar (EtOAc; n-BuOH) and non polar (nhexane; dichloromethane) fractions from the bark of Persea cordata, against guinea pig ileum contracted by 5-hydroxy...
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The effects of essential oil of Croton nepetaefolius (EOCN) on guinea-pig-isolated ileum were studied. We previously demonstrated that EOCN induced reversible relaxation of ileal tone artificially increased by high [K(+)] nutrient solution. This study aimed to elucidate whether these effects were caused by indirect, neural, or primarily by myogenic effect. EOCN (40 microg/mL) induced a relaxati...
متن کاملAntispasmodic Effects of Some N-substituted 2- Methyl Imidazole Derivatives on Guinea Pig Ileum
A series of novel N-substituted 2-methyl imidazole derivatives have been synthesized, and their in vitro antispasmodic activity was assessed on contractions of isolated guinea pig ileum, induced by acetylcholine (5× 10M to 1× 10M), and compared with the effect of atropine. All the prototypes were synthesized and confirmed by their FTIR, HNMR, MASS and elemental spectral data. Antispasmodic acti...
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• sistema gastro intestinal: aumenta a secreção gástrica e sua acidez, laxativo; • rim: diurético, usado nas nefrites agudas e nas uremias (aumenta a excreção de amônia); • vasos sanguíneos: hemorróidas, varizes e reumatismo; • obesidade: auxiliar nos regimes de emagrecimento; • diabetes: hipoglicemiante, auxiliar nos regimes de emagrecimento; • combate a anemia, raquitismo; • diminuição do col...
متن کاملAntihistaminic activity of carane derivatives in isolated guinea pig ileum.
Local anesthetics (LAs) inhibit membrane depolarization by reducing sodium and potassium conductance, and subsequent displacement of calcium ions from binding sites seems to occur. Histamine release appears to be a secretory process in which calcium couples the stimulus to the exocytosis of histamine-containing granules. Furthermore, LAs are structurally similar to histamine H(1)-receptor antag...
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ژورنال
عنوان ژورنال: Biological and Pharmaceutical Bulletin
سال: 2005
ISSN: 0918-6158,1347-5215
DOI: 10.1248/bpb.28.902